ethyl 5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate

ethyl 5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate - Names and Identifiers

Name	ethyl 5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate
Synonyms	ethyl 5-oxo-1,2-dihydropyrazole-3-carboxylate ethyl 5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate 2,5-Hihydro-5-oxo-1H-pyrazole-3-carboxylic acid ethyl ester 1H-Pyrazole-3-carboxylic acid, 2,5-dihydro-5-oxo-, ethyl ester
CAS	40711-33-9

ethyl 5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate - Physico-chemical Properties

Molecular Formula	C6H8N2O3
Molar Mass	156.14
Density	1.272±0.06 g/cm3(Predicted)
pKa	7.78±0.70(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

ethyl 5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate - Upstream Downstream Industry

Raw Materials

ALPHA-CHLOROFUMARICACIDDIETHYLESTER
Diethyl acetylenedicarboxylate
4,4,4-TRICHLOROACETOACETIC ACID ETHYL ESTER
2,5-dihydro-5-oxo-1H-pyrazole-3-carboxylic acid
Semicarbazide hydrochloride
Sodium acetate
Ethanol
HYDRAZINE
Diethyl oxalacetate

ethyl 5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate - Introduction

ethyl 5-oxo-5-dihydro-1h-pyrazole-3-carboxylate (ethyll 5-oxo-2, is an organic compound.). The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Colorless to light yellow liquid
-Molecular formula: C8H9N3O4
-Molecular weight: 215.17g/mol
-Melting Point: no fixed melting point, will decompose
-Boiling point: 376.8 ℃
-Density: 1.384g/cm³
-Solubility: Soluble in organic solvents such as ethanol and chloroform

Use:
-5-oxo-2, 5-dihydro-1h-pyrazole-3-carboxylic acid ethyl ester has certain biological activity in the pharmaceutical field and can be used as a pharmaceutical intermediate for the synthesis of other compounds.
-It can also be used as a component of dyes and coatings, with the properties of pigments and plasticizers.

Method:
-5-oxo-2, 5-dihydro-1h-pyrazole-3-carboxylic acid ethyl ester can be synthesized by the following steps:
1. The p-Toluenesulfonyl Ester and ethyl pyruvate are reacted under alkaline conditions to generate 5-methyl -2,5-dihydro-1H-pyrazole-3-carboxylic acid ethyl ester.
2. The compound generated in the previous step is reacted with benzoyl peroxide under acidic conditions, and the carboxyl Oxo and esterification reactions occur to obtain the final product 5-oxo-2, ethyl 5-dihydro-lh-pyrazole-3-carboxylate.

Safety Information:
-5-oxo-2, 5-dihydro-1h-pyrazole-3-carboxylic acid ethyl ester can generally be regarded as a safe compound under reasonable use. However, it is still a chemical and requires some safety precautions to be taken:
-Wear appropriate protective equipment such as lab gloves and goggles during handling and handling.
-Avoid contact with skin and eyes. If in contact, rinse with plenty of water immediately.
-Use in a well-ventilated environment to avoid inhaling its vapors.
-Store away from fire and oxidizing agents.
-Read and follow the safe operation manual and instructions for the relevant chemicals before use.

Please note that the safety of any chemical substance depends on the way it is used and handled. When using or handling chemicals, the relevant safety procedures should be strictly observed, and professional chemical personnel or relevant institutions should be consulted for more detailed safety information.

Last Update：2024-04-09 20:45:29